Posterous theme by Cory Watilo

Filed under: biomath

You've heard of Illiteracy. Here's Innumeracy.

I don't know how to introduce this video "Verizon Math Fail" (embedded below) blog. It's been around for a while, so you may have heard about it or seen it.

The piece is less than three minutes long and is full audio, so it should load very quickly in your browser. Give it a listen.

Think about this for a second. We've stumbled upon some innumeracy that rises to the institutional level. Two people at this customer service center can't wrap their heads around this problem. And, according to the blog, Verizon continues to misrepresent the cost of the service that is causing this problem. If this is true, can you imaging how many people had to sign off on the mistake? It boggles the mind.

I like to point out to people that rarely will someone say to a total stranger, "I suck at reading and writings" but often people don't think twice about saying, "I'm bad at math." This says something about our society, doesn't it. If it's true that America's economic competitiveness rests in part on having a scientifically and mathematically literate (if not sophisticated) workforce, than we need to be afraid.

For more discourse on the topic of numeracy and innumeracy, check out these books by John Allen Paulos:


Both are interesting reads for anyone.

Disclaimer: I recommend these books because I've read them and they had an impact on me. My interest in recommending these or other items is not financial. It stems from my desire to draw more people into the study of science and mathematics.

America needs more Scientists and Mathematicians. But are we STEM-folks hurting our cause?

This post is inspired by the overblown and overhyped forecasts of American major media (and government) meteorologists. their recommendations regarding severe weather and dangerous travel have always seemed hyperbolic to me. Then, when I read the Discovery.com blog post here, I felt one of my buttons pushed, and I had to express this exasperation somewhere. Here's the quote from the post that set me off:

I certainly hope that no one will be killed or injured from this, but I also know that there will always be people who don’t heed the warnings. If only more people understood that science works, and that geologists and volcanologists know their stuff. They devote their lives to this field, and their study of the Earth and its paroxysms may save the lives of others.

When I read this, I certainly empathized with the author and could project sympathy and concern for the residents of Legzapi, Philipines whose lives were threatened by the volcano, Mayon. However, the text is a nice example of a rhetorical flourish aimed at the non-scientific populace that, in the long term, contributes to the widening of the divide between those who appreciate the contributions of science to society and those who are frustrated by the empty day-to-day promises made by science to America.

This idea that "there will always be people who don’t heed the warnings" of scientists who "know their stuff" about predicting natural disasters concerns me. Surely, the geologists and volcanologists who are monitoring Mayon are making their recommendations regarding evaluation and so forth with the best possible intentions. But let's look to meterologists in the United States as examples of scientists who "know their stuff" and who make recommendations to the general populace through local and national media. Are they scientists who make their recommendations on the basis of cutting-edge technology and data-based decision making? Do they make measured and reasonable recommendations on the nightly and 24/7 channels?

If we could do a better job of making science relevant and beneficial to the day-to-day American, maybe we could encourage more young people to pursue educational and career paths toward science and mathematics. And this is what America needs -- the new economic and philosophical patriotism is a devotion to the study and implementation of skill and talent in science, technology, engineering, and mathematics (STEM). But we won't be able to turn the hearts of America in this direction without helping them to understand its benefits and how it can positively impact peoples' day-to-day living.

This short post (a rant, really), can't do this issue justice. It's just SOOO big. But the article that inspired this reveals a slice of what's wrong with the American perception of STEM and how it serves (or fails to communicate truthfully and effectively) society and its needs.

Quantitative Cell Biology Summer Program

Here's a great opportunity for undergraduates who are interested in interdisciplinary experiences that have connections with the life sciences. Please note that this program is open to students outside of just the mathematical and life sciences. Instead of repeating the information here, I'll let you read for yourself.

---------------------------

From: "Huber,Greg"
Date: November 30, 2009 5:16:18 PM CST
To: "SIGMAA-BIO@LISTS.MAA.ORG"
Subject: Quantitative Cell Biology Summer Program


This summer internship opportunity may be of interest to junior-year students and their advisors.

=======================================================

The Center for Cell Analysis & Modeling (CCAM), located in the School of Medicine at the University of Connecticut, is accepting applications through March 2010 from undergraduate students interested in a summer fellowship at the interface between math, computer science, physics, chemistry and cell biology.

Internships will be awarded at a stipend level of $4000 for 10 weeks from early June through mid August. Applicants should be finishing their junior year and should submit a letter of application describing their past experience, what kind of research interests them, and why they are interested in CCAM.

Please share this information with your students and colleagues.

More information and how to apply can be found at our website:

http://www.ccam.uchc.edu/cam/cam_internships.html

If you have any questions, feel free to contact me.


- Greg Huber

tel: 860-679-4209
email: huber@uchc.edu

On Undergraduate Computational Biology and the Biology Curriculum

As a mathematics professor at a 'primarily undergraduate institution' (a.k.a. PUI) who has been deeply involved in some local and national efforts at reforming undergraduate biology and mathematics education to be more interconnected, I delight at coming across papers with titles like this one: "Computing Has Changed Biology—Biology Education Must Catch Up" by Pavel Pevzner and Ron Shamir (Science 31 July 2009: Vol. 325. no. 5940, pp. 541 - 542). Often times, papers like these are written by people who are passionate about STEM education reform, and they share in their writings insights and perspectives that are useful to me.

This is not really one of those papers. In this article, the authors make an ineffectual argument for changing the undergraduate biology curriculum to include more training in computational biology, a.k.a. bioinformatics. It's not that what they want isn't reasonable or that it's not needed. The authors do want to reform the undergraduate biology curriculum in a meaningful way. It's just that this note in the Education Forum of Science is more of an excuse to report on a conference: RECOMB Bioinformatics Education Conference (http://casb.ucsd.edu/bioed/). Mostly, the authors repeat many of lines we've heard from many others since the publication of Bio2010.

This article does give some decent concrete ideas for how a computational biology course would be designed. For example, a course could introduce the computational content/concepts in the context of framing questions such as "Did our ancestors interbreed with Neanderthals?" or "How do we distinguish between different forms of breast cancer and choose the appropriate chemotherapy?" or "How can biomarkers be used to predict clinical outcomes of young breast cancer patients?" But the authors don't go far beyond that. And this kind of suggestion, of teaching new concepts in a context that is immediately meaningful to students, is not innovative or new; educators that specialize in how students learn and in broadening participation in science and mathematics (cf. the BioQuest Curriculum Consortium at http://bioquest.org) have been recommending this approach for many years,

That the authors are ignorant of the work others have done in student learning and pedagogy reform is understandable (though not necessarily excusable, given the aim of this article). That I don't understand is the authors' apparent ignorance of or indifference to the challenge of adding anything to the standard undergraduate biology curriculum. Degree programs in the life sciences are already tight, and requirements set by admissions to medical schools further limit program flexibility (like it or not). Perhaps the recent AAMC/HHMI Committee report “Scientific Foundations for Future Physicians” (see http://www.hhmi.org/news/SFFP20090604.html) will lead medical school admissions committees to raise their expectations of applicant competence in mathematics, statistics, and computation. Such a move would open the possibility of biology programs requiring the type of new course proposed by Pevzner and Shamir. But even if medical schools calls for more quantitative sophistication (or literacy) from medical school candidates, we should ask if a course in bioinformatics should be required of all biology majors. That's a discussion I'll leave for others and for later.

In the end, the authors say that implementing their so-called proposed course "may become a first step toward building the new computational curriculum for biologists" without ever proposing a concrete course. At best, they give the readers the "pedagogical challenge" of designing this course so that it "(i) assumes few computational prerequisites, (ii) assumes no knowledge of programming, and (iii) instills in students a meaningful understanding of computational ideas and ensures that they are able to apply them." At worst, they come across as people who have little knowledge of or appreciation for the tightness of the undergraduate biology curriculum They can parrot the spirit of Bio2010 well, but they're not offering much meat for those of us who are in the trenches trying to make things happen.

Before closing, I'm going to pick a nit with their imperial use of the adjective 'computational' when used to modify 'biology.' While many people have used the terms 'bioinformatics' and 'computational biology' interchangeably. This was reasonable at a time when genomics led the way in leveraging computational and algorithmic power to illuminate questions in biology. But now applications of computation can be found in every corner of in the life sciences. Agent-based models illuminate ecosystem dynamics. CompuCell's pde-based methods are used to model cellular phenomena. Computer-assisted tools use mathematical models of shape and image-analytic techniques to understand medical images. These are just a couple examples that have come up in Truman's undergraduate mathematical biology program. Each of these are examples of 'computational biology', where computational is used in its broadest sense to mean an application of computers and computational methods. Let's relegate the synonymous use of 'bioinformatics' and 'computational biology' to the history books with a nod and a thanks.

With all that said, and as much as the article didn't thrill me like Joel Cohen's "Mathematics Is Biology's Next Microscope, Only Better; Biology Is Mathematics' Next Physics, Only Better" (see http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.0020439), the short article is worth reading, if only to see that there are many people out there who want undergraduate curricular reform. And the references are decent.